Why are women's health issues often brushed off as “just part of aging”?
In this eye-opening episode, Natassia sits down with board-certified family nurse practitioner, women's longevity and sexual medicine expert Jackie Giannelli to unpack the truth about perimenopause, menopause, libido, hormone replacement therapy, GLP-1 medications, hair loss, testosterone, vaginal estrogen, peptides, and sexual wellness. They explore why so many women feel dismissed when experiencing brain fog, fatigue, low desire, anxiety, and disrupted sleep and what can actually be done about it.
From the controversy surrounding hormone therapy and breast cancer fears to the surprising effects of GLP-1 medications on libido and pleasure, this conversation challenges outdated medical narratives and offers practical insights for women who want to reclaim their vitality, confidence, relationships, and long-term health. If you've ever wondered whether feeling “flat” is normal, this episode may change the way you think about aging and wellness.
00:00 – Welcome and introduction
01:15 – Why women feel dismissed by healthcare
02:58 – The first signs of perimenopause
05:25 – Sleep, libido, brain fog, and hormone decline
06:25 – Normal vs. optimal hormone levels
09:41 – Medical gaslighting and menopause care
11:32 – When hormones aren't the whole story
13:05 – Testosterone therapy for women
15:03 – Understanding estrogen, progesterone, and hormone balance
17:28 – Bioidentical vs. synthetic hormones
19:19 – The Women's Health Initiative controversy
22:04 – Breast cancer fears and hormone therapy
24:52 – Feeling flat, dopamine, and SSRIs
26:10 – GLP-1 medications and sexual side effects
29:20 – Combining hormones with GLP-1 treatment
32:08 – Long-term concerns about GLP-1 medications
36:12 – Hair loss, hormones, and weight loss drugs
41:37 – Peptides explained
44:01 – The peptide regulation gray area
46:00 – PT-141, Addyi, and female libido treatments
51:16 – Why vaginal estrogen is underused
54:13 – Designing a home for intimacy and connection
57:08 – The science of music and arousal
59:00 – Closing thoughts
Follow Jackie Giannelli on Instagram
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