Big-cap stocks aren’t always the fastest growers—sometimes their size slows them down. But two giants are defying the trend: Teledyne, with 12% annual revenue growth and strong margins, and Gilead Sciences, leveraging scale to boost margins and free cash flow. Meanwhile, General Dynamics, known for tanks and steady growth, may be hitting a wall as demand slows and earnings lag. Smart management can turn size into strength—or expose weaknesses.

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