FFP 638 | Sperm DNA Damage and Recurrent Miscarriage

Lisa breaks down a research paper on sperm DNA fragmentation and its link to recurrent first-trimester miscarriage. The study found that most men classified as "normal" under the WHO 2021 semen analysis criteria still had elevated DNA fragmentation, and that double-stranded DNA damage specifically was tied to miscarriage risk. Lisa explains why standard semen analysis may miss this issue, why ICSI doesn't necessarily solve it, and why couples facing unexplained or recurrent loss may benefit from pushing for deeper sperm testing.

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