Welcome to Episode 06 of Skin As It Should Be Podcast! In this conversation, host Geoff Paton interviews master chemist Trevor Steyn about the evolving field of microbiome skincare, focusing on live biotherapeutics, postbiotics, and related technologies.
Trevor highlights regulatory hurdles, misuse of the term “probiotic,” and emerging innovations like encapsulation, phage therapy, and AI-driven personalized treatments. They explore the differences between genetically engineered microbes used as drugs and naturally occurring microbes in over-the-counter products, as well as the challenges of maintaining live microbes in formulations.
He concludes with optimism about the future of microbiome skincare, while acknowledging ongoing technical and economic challenges. This episode unpacks the actionable guidance for consumers, formulators, and industry professionals navigating this rapidly evolving space.
⏱ Timestamped Overview
00:13 - The Two Paths for Live Biotherapeutics
01:16 - Misuse of the Term "Probiotics" in Skincare
02:51 - Drug Path: Companies and Technologies
06:08 - Safety Mechanisms in Genetically Engineered Microbes
07:58 - Over-the-Counter Path: Naturally Occurring Microbes
10:05 - Encapsulation and Delivery Technologies
12:41 - GRAS and Non-GRAS Species Explained
16:46 - Legal Actions and Regulatory Crackdown
18:26 - Techniques for Maintaining Live Microbes
22:25 - Live vs. Dead Microbes: Efficacy
27:13 - Light-Based Microbiome Manipulation
30:02 - Precision Biotherapeutics and AI
34:17 - Barriers to Everyday Adoption
💬 Quote of the Episode
“We see much higher benefits with live microbes.” – Trevor Steyn
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