Chirag Patel is an Associate Professor of Biomedical Informatics at Harvard Medical School, renowned for his expertise in using computational methods to understand human health and disease from high-throughput data streams. He specializes in understanding the role in the intersection of genetics and environmental exposures (the exposome) in human health, as well as various disease areas such as diabetes, cardiovascular disease, and Alzheimer’s disease.
CONTACT RANDY:
Feedback: metasciencematters@gmail.com
EPISODE LINKS:
Chirag’s Lab: https://www.chiragjpgroup.org/
TEDx talk on the exposome: • Exposome: decoding human health and diseas...
OUTLINE:
0:00 - Introduction
0:37 - How do you decide what to work on?
1:57 - Where does metascience fit into your work?
3:57 - Vibration-of-effects analysis
6:41 - How does VoE change how we see existing scientific work?
9:22 - The biggest challenges in the replication crisis within biomedical informatics
11:48 - Environment-wide association study of Type 2 diabetes
15:04 - The exposome
17:30 - Policy vs. precision medicine applications of the exposome
20:09 - The patient exposome
22:38 - HBA1C for diabetes as a bridge to the exposome
23:54 - Broader metascientific issues of the exposome
25:01 - The effects of extreme weather events on human health
29:35 - AI for biomedical informatics, the exposome, metascience
31:19 - Advice for listeners interested in pursuing research like Chirag’s
32:53 - Outro
