Remember that animated gem Osmosis Jones? The Bill Murray and Chris Rock flick that bombed at the box office with just $14 million against a $70 million budget, despite years in development and a bold concept of cops inside the human body. Critics were split — even Roger Ebert gave it a glowing 3/4 stars — but audiences stayed away. Its failure didn’t just hurt the film; it helped kill Warner Bros. Feature Animation. A cautionary tale: big names and wild ideas don’t guarantee success in Hollywood.

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