The 49ers’ defense is primed for a breakout performance against the Dolphins, targeting QB Malik Willis—already sacked five times this season—who’s been holding the ball too long and struggling with Miami’s shaky offensive line. With Nick Bosa leading the charge and Osa Odighizuwa disrupting the pocket, San Francisco’s pass rush could finally turn things around after a frustrating Rams game. Rested and hungry, they’re in prime position to dominate the stat sheet and force turnovers.

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