With Dr. Abraham Morgentaler and Dr. Marianne Brandon
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In this episode, Dr. Brandon and Dr. Morgentaler are joined by special guest Dr. Alan Altman to discuss how the Women's Health Initiative reshaped menopause care, why hormone replacement therapy was misunderstood for decades, and the evidence that has helped restore confidence in estrogen treatment.
00:00 – Meet Dr. Alan Altman – Dr. Alan Altman joins the podcast to share how he became one of the leading voices challenging misconceptions about hormone replacement therapy.
01:56 – WHI Fallout and FDA Shift – Dr. Altman explains how the Women's Health Initiative created decades of fear around HRT and why recent FDA actions have begun correcting the record.
02:52 – Aspen Story: Hot Flash Havoc – A patient encounter in Aspen inspired Dr. Altman to educate women through the documentary Hot Flash Havoc and fight menopause misinformation.
07:41 – How He Entered Menopause Care – Dr. Altman shares how his wife's menopausal symptoms sparked his lifelong passion for menopause and sexual medicine.
14:37 – Life Before and After WHI – Learn how menopause treatment changed dramatically after WHI and why fear replaced evidence in hormone therapy decisions.
20:09 – What WHI Got Wrong – Dr. Altman breaks down the biggest flaws in the WHI interpretation and why age-specific data completely changed the story.
Resources: Rossouw JE, et al. Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial. JAMA. 2002;288(3):321-333. https://doi.org/10.1001/jama.288.3.321
Manson JE, et al. Menopausal Hormone Therapy and Long-term All-Cause and Cause-Specific Mortality: The Women's Health Initiative Randomized Trials. JAMA. 2017;318(10):927-938. https://doi.org/10.1001/jama.2017.11217
U.S. Food and Drug Administration (FDA). Joint Meeting of the Bone, Reproductive and Urologic Drugs Advisory Committee and the Drug Safety and Risk Management Advisory Committee on Low-Dose Vaginal Estrogen Products. (2024)
Connect with Dr. Alan G Altman: https://www.herdesire.net/assets/bios/altman.php
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