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Episode 108 - Single MALT | Marginal Zone Lymphoma

Dela

What do you call a small B-cell lymphoma that isn't CD5 positive, isn't CD10 positive and generally refuses to wear any of the usual hats? Probably marginal zone lymphoma. Possibly. Maybe.

Join the Bloody Minded crew as we head to the edge of the follicle where the bloodstream's customs officers live, and look at what happens when they go rogue. Discover how to cure a cancer with a PPI, and why we're so very bored of the NF-κB pathway.

TIMESTAMPS

0:57 - Whisky sponsorship pls and thx
2:11 - What the marginal zone is/isn't 
6:28 - Marginal zone B cells
8:35 - Classifying marginal zone lymphoma
11:05 - Epidemiology
12:09 - Pathophysiology in gastric MALT
16:42 - Stimuli for other marginal lymphomas
19:55 - Pathological features of marginal
21:20 - Splenic MZL
25:43 - Flow cytometric features
30:13 - Workup of MZL
32:20 - Management strategies
37:53 - Prognosis
38:56 - High grade transformation
40:07 - Take home messages

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