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Episode 103 - On The Wards: Breaking Bad . . . Cells | Tumour Lysis Syndrome

Dela

Have you been asked to review “TLS” bloods?? Are you concerned the nursing staff are pranking you with haematology bloods that don’t include a FBC or coags? Why could you possibly want to look at something that isn’t a cell count? What crazy person decided after hours bloods needed to be collected on ICE? And WHY ?!?! Join us for an On The Wards approach to dealing with those TDS TLS SOS calls.

TIMESTAMPS:

0:56 - The team breaking stuff
3:40 - Episode overview
5:07 - Setting the scene
6:33 - The history of TLS
7:28 - (nailed it)
8:00 - Pathophysiology of TLS
10:41 - Mechanisms of renal injury in TLS
11:39 - Clinical consequences of TLS
12:46 - Diagnostic criteria in TLS
15:10 - Clinical TLS vs lab TLS
15:35 - Grading TLS
16:55 - Other clues of TLS
18:09 - Who is at risk of TLS?
23:15 - Prevention of TLS
24:27 - Allopurinol
26:58 - Rasburicase
33:03 - Fluids fluids fluids
33:44 - Deciding who gets prophylaxis
35:50 - What ARE TLS bloods?
36:31 - What to do with a TLS on the ward
40:05 - Take home messages

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