Most people know about BRCA1 and BRCA2…
But what about the other gene mutations that increase breast cancer risk and could shape your treatment and prevention plan?
In this video, I’m breaking down two under-recognized but important players:
🔬 CHEK2: an inherited genetic mutation that affects DNA repair and raises the risk for breast, colon, and prostate cancer
🧬 PIK3CA: an acquired mutation found in up to 40% of HR-positive, HER2-negative breast cancers, now guiding the use of new targeted therapies
If you’ve had breast cancer, have a family history, or want to understand your genetic testing results, this is a must-watch.
You'll also learn how to support your body even with mutations with functional and lifestyle strategies.
📌 Topics covered:
• Germline vs somatic mutations
• CHEK2 mutation symptoms & risk
• PIK3CA and the latest treatment advances
• How to reduce cancer risk naturally—even with mutations
• Why genetic testing panels should go beyond BRCA
🔗 Sources referenced:
• https://ascopost.com/news/may-2025/inavolisib-based-regimen-in-pik3ca-mutated-hr-positive-her2-negative-advanced-breast-cancer/
• https://today.ucsd.edu/story/to-study-cancer-kill-switch-uc-san-diego-scientists-will-send-stem-cells-to-space
• https://vhio.net/2025/05/31/triplet-combination-as-a-new-treatment-option-in-pik3ca-mutated-locally-advanced-or-metastatic-breast-cancer
• https://pubmed.ncbi.nlm.nih.gov/22058428/
WAYS TO CONNECT
📷IG https://www.instagram.com/laurenmcranmer
🤍IG https://www.instagram.com/afterthebellhealing
✉️ lauren@afterthebellhealing.com
Start Healing ➡️ https://www.afterthebellhealing.com
VIDEO DETAILS
Camera: https://amzn.to/3XnFQme
Free Music for Videos 👉 Music by cold winter breeze - starry nights - https://thmatc.co/?l=1A95B49B
DISCLAIMER: This is not medical advice. The information provided is for informational and educational purposes only. It does not substitute for professional medical advice. It is not intended to diagnose or treat any physical or psychological health condition.
These are my own opinions from my own experiences.
Links above are affiliate links. This means I receive a commission through purchases. This does not affect you as a consumer.