Lupus put her in the ICU in college. She came back to run 14 marathons, 5 ultras, and 200 miles from Boston to NYC.
Run coach Mireille Siné on training with autoimmune disease — flares, fatigue, and the mindset shift that changes everything.
In this episode of Invisible Strength, Karin and Chris talk with Mireille Siné — certified run coach, AIP nutrition coach, and the first Black woman to run 200 miles from Boston to New York City.
Mireille shares her full story: the college stress that preceded her lupus diagnosis, the blood clot that took three ER visits to catch, chemotherapy and medical leave, and the slow, deliberate comeback that started with a quarter-mile run.
We get practical: how Mireille structures training around flares with her stoplight protocol, why sleep is her non-negotiable recovery anchor, how she approaches nutrition and meal prep for inflammation, and how to tell normal training fatigue from the start of a flare.
Plus the mental game — why "you're not gonna get anywhere chasing a ghost," and what invisible strength means to her.
✨ FREE QUIZ: Not sure where to start on your own health journey? Take our free quiz → https://invigorateyourjourney.com/quiz/
⏱️ CHAPTERS
00:02 Meet Mireille
02:02 Training with compassion
04:08 The lupus diagnosis story
09:14 Coming back: the first mile
13:04 Self-doubt and setbacks
16:01 The marathon that means the most
22:01 Sleep, nutrition, community
26:54 Coaching autoimmune athletes
30:23 The stoplight protocol for flares
34:14 Fatigue vs. flare: how to tell
35:39 "Chasing a ghost" — the mindset shift40:44 What invisible strength means42:25 What's next for Mireille
🌱 Community, resources & coaching: https://www.invigorateyourjourney.com
🏃🏾♀️ Mireille: @heycoachmireille and https://www.coachedbymireille.com/
🎧 Subscribe for real conversations around: Lupus, autoimmune disease, chronic illness, healing, fatigue, mindset, movement, resilience, and invisible illness support.
💬 COMMENT BELOW: What's something people don't understand about living with chronic illness?
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⚠️ Disclaimer: This content is for education and shared experiences only and is not medical advice. Always consult your healthcare team before making changes.
