Oestrogen is the headline act in menopausal hormone therapy, but the way it is delivered matters.

In this episode, we explore the differences between oral and transdermal oestrogen, including patches, gels and tablets. We look at absorption, first-pass metabolism, clotting risk, practical counselling points, dose considerations and why one formulation may suit a patient better than another.

Using our hormone girl-band analogy, Beyoncé is oestrogen, but whether she arrives through the front door or the stage door changes what happens backstage.

We also discuss body-identical oestradiol, when transdermal therapy may be preferred, common application errors and why patients with a uterus usually need adequate endometrial protection alongside systemic oestrogen.

This episode is designed for pharmacists and other clinicians wanting a practical, evidence-based overview of oestrogen prescribing and counselling in menopause.



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