Patients with MASLD often underreport alcohol use and even modest intake can block improvement. Drs VanWagner and Ajmera share practical tools to quantify intake, spot MetALD, and counsel patients effectively.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/ca8/p04/podcast-masld-s1-ep2-2026a1000aau. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Metabolic Dysfunction-Associated Steatotic Liver Disease and Steatohepatitis https://reference.medscape.com/cc2/p10/global-consensus-recommendations-metabolic-dysfunction-2025a1000iy5#1

Is Moderate Alcohol Use in Nonalcoholic Fatty Liver Disease Good or Bad? A Critical Review https://pubmed.ncbi.nlm.nih.gov/28100008/

Practical Guide, Challenges, and Pitfalls in Liver Fibrosis Staging https://pubmed.ncbi.nlm.nih.gov/37536882/

Among Patients With Nonalcoholic Fatty Liver Disease, Modest Alcohol Use Is Associated With Less Improvement in Histologic Steatosis and Steatohepatitis https://pubmed.ncbi.nlm.nih.gov/29378307/

A Multisociety Delphi Consensus Statement on New Fatty Liver Disease Nomenclature https://pubmed.ncbi.nlm.nih.gov/37363821/

Phosphatidylethanol in Steatotic Liver Disease https://pubmed.ncbi.nlm.nih.gov/40759197/

Phosphatidylethanol and Self-Reported Alcohol Intake to Subclassify Individuals at Risk of Steatotic Liver Disease: An Analysis of Data From a Prospective Cohort Study https://pubmed.ncbi.nlm.nih.gov/40945520/

The AUDIT Alcohol Consumption Questions (AUDIT-C): An Effective Brief Screening Test for Problem Drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test https://pubmed.ncbi.nlm.nih.gov/9738608/

Elevated ALT/AST Ratio as a Marker for NAFLD Risk and Severity: Insights From a Cross-Sectional Analysis in the United States https://pubmed.ncbi.nlm.nih.gov/39253584/

Alcohol Use Disorder: A Comparison Between DSM–IV and DSM–5 https://www.niaaa.nih.gov/publications/brochures-and-fact-sheets/alcohol-use-disorder-comparison-between-dsm

Wilson Disease https://emedicine.medscape.com/article/183456-overview


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