Week 1 of the 2026 fantasy football season is here, and the matchups are already creating some major start/sit decisions. We break down the most important Week 1 fantasy football matchups at QB, RB, WR and TE including the players you can start with confidence, the tough decisions you need to think twice about, and the late-round/waiver-wire options who could surprise this week. We'll also cover the latest injury situations, betting-market signals, matchup data and the players whose rankings should move based on what we know heading into Sunday.
Join the 4for4 Discord! ➡️ discord.gg/4for4 ✅ Use Promo Code "YOUTUBE" to save 25% off a 4for4 Subscription 👉🏼 https://www.4for4.com/plans ============================= Connect with us! ============================= Follow Caleb on X ➡️ https://x.com/CalebNiemi_ Follow Addison on X ➡️ https://x.com/AddisonHayes_ Follow John on X ➡️ https://x.com/4for4_John Follow 4for4 on X ➡️ https://x.com/4for4football ============================= ⏰Timecodes⏰ 00:00 - Week 1 Is Finally Here
01:03 - What We Learned From the First Two Games
06:40 - Week 1 Injury Updates
13:56 - Quarterback Matchups
30:55 - Running Back Matchups
46:23 - Wide Receiver Matchups
01:07:27 - Tight End Matchups
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