This Week in Nephrology — May 21, 2026

Welcome to This Week in Nephrology. This week we're covering 10 notable papers spanning new therapeutic approaches in complex kidney diseases, innovations in diagnostics, and key considerations for transplantation in older adults. Let's dive in.

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This week's papers: 1. Deceased Donor Kidney Transplantation Versus Continued Dialysis Among Patients Aged 75 Years or Older: A Target Trial Emulation. — American journal of kidney diseases : the official journal of the National Kidney Foundation 2026 2. Gene-disease relationships for glomerular phenotypes: expert recommendations from ClinGen. — Nature reviews. Nephrology 2026 3. CRT-Estimands Framework: consensus based extension of the ICH E9(R1) addendum for cluster randomised trials. — BMJ (Clinical research ed.) 2026 4. Urinary fluorogenic reporters for noninvasive detection and staging of kidney fibrosis. — Science translational medicine 2026 5. Nondialyzable versus Dialyzable Beta-Blockers in Hemodialysis: A Target Trial Emulation Study. — Journal of the American Society of Nephrology : JASN 2026 6. Daratumumab Monotherapy versus Bortezomib-Based Regimens in frail patients with Biopsy-Proven Renal AL Amyloidosis. — Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2026 7. DUAL GIP/GLP-1Ra reduces residual proteinuria in non-diabetic fabry disease. — Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2026 8. Implementing the commitments of the World Health Assembly kidney health resolution: a key opportunity to improve health for millions. — Lancet (London, England) 2026 9. Loss of Cyclin G-Associated Kinase (Gak) Leads to Lysosome Dysfunction and Immune Modulation in Podocytes. — Journal of the American Society of Nephrology : JASN 2026 10. Kidney biopsy during pregnancy: indications, complications, results and therapeutic impact. — Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2026

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