The potential for mRNA vaccines to cause cancer
Theoretical mechanisms
DNA Integration
mRNA or fragments, reverse transcriptase, potentially disrupting tumour suppressor genes or activating oncogenes
DNA contamination, integrate into the genome
Contaminants in Vaccine Production
Pfizer COVID-19 modRNA vaccines also contained an SV40
Inactivated tumour suppressor genes, p53 and Rb, promoting unchecked cell growth
Prolonged Spike Protein Expression
N1-methyl-pseudouridine-modified mRNA encoding the SARS-COVID-19 Spike protein
Lipid nanoparticle (LNP) delivery to stem cells
Sustained spike protein production,
induce chronic inflammation,
disrupt cellular repair mechanisms.
Immune Suppression or Dysregulation
Molecular Mimicry, Autoimmunity, inflammation
Alter regulatory T-cell function, (potentially allowing pre-existing cancers to progress).
(If the spike protein shares epitopes with tumour suppressor proteins)
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