I've been getting Botox on and off since I was 38. I never once thought about what it might mean for my brain until another APOE4 carrier asked me directly. So I went looking for the research. What I found wasn't the verdict I expected in either direction, it was a genuine gap. This episode walks through what the actual studies say, where they contradict each other, why dose and route matter more than headlines suggest, and how I made a decision without getting the certainty I wanted.
This episode breaks from the usual protocol format, there's no clean "here's what works" takeaway. Instead I trace how I went looking for evidence that cosmetic Botox affects the brain in someone with my genetics, and ended up with a research gap instead of an answer. I cover the biological reasons APOE4 carriers have a different baseline worth asking about, walk through the specific studies that pointed in different directions, explain how dose and exposure route changed my read of the evidence, and get honest about the fact that vanity, not brain safety, is what actually got me back in the chair.
Podden och tillhörande omslagsbild på den här sidan tillhör
Sarah Kuhn. Innehållet i podden är skapat av Sarah Kuhn och inte av,
eller tillsammans med, Poddtoppen.
