Neuroscience Daily for 27 September follows 3 stories from r/neuro and r/neuroscience, moving through childhood epilepsy, riluzole and glia, brain as computer.
Chapters
00:00:00 — Intro
00:00:10 — Childhood Epilepsy
00:01:12 — Riluzole And Glia
00:02:16 — Brain As Computer
00:03:08 — Closing
1. Childhood Epilepsy
This story is about how human brain organoids are revealing a possible cause of childhood epilepsy, in a study published by Nature. Researchers modeled tuberous sclerosis complex by removing both copies of the TSC2 gene in selected human brain cells, then tracked what happened as the organoids developed.
The second story concerns riluzole and memory in a rat model of Alzheimer’s-related toxicity, reported in the Journal of Neuroinflammation. Researchers injected amyloid-beta oligomers into the hippocampal CA1 region of male rats and gave the animals riluzole for seven days.
The final story asks whether the brain is really best understood as a computer, in a review from Cognitive Wonderland discussing Romain Brette’s book The Brain, In Theory. The argument is that the computer comparison can quietly make researchers treat the brain as a passive device that receives inputs, while unexplained activity gets labeled noise.
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