Atypical Myopathy

In this episode of Current Vet, Dr. Lottie talks about equine atypical myopathy, how sycamore toxins disrupt muscle energy metabolism, why the condition is an EMERGENCY, the key clinical signs to recognise and how to manage affected horses and their co-grazers.

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Timeline:
00:00 Intro
00:45 Case
02:32 Aetiology & Pathogenesis
05:29 Clinical Signs
09:40 Diagnosis
15:11 Treatment
20:15 Prevention
22:02 Key Points
23:45 Outro

References

• Żuraw, A. et al. (2016) ‘Equine atypical myopathy caused by hypoglycin A intoxication associated with ingestion of sycamore maple tree seeds’, Equine Veterinary Journal, 48(4), pp. 418–421. Available at: https://doi.org/10.1111/evj.12460.
• Votion, D.M. et al. (2019) ‘Potential new sources of hypoglycin A poisoning for equids kept at pasture in spring: a field pilot study’, Veterinary Record, 184(24), pp. 740–740. Available at: https://doi.org/10.1136/vr.104424.
• van GALEN, G. et al. (2012) ‘European outbreaks of atypical myopathy in grazing horses (2006–2009): Determination of indicators for risk and prognostic factors’, Equine Veterinary Journal, 44(5), pp. 621–625. Available at: https://doi.org/10.1111/j.2042-3306.2012.00555.x.
• Sander, J. et al. (2016) ‘Rapid diagnosis of hypoglycin A intoxication in atypical myopathy of horses’, Journal of Veterinary Diagnostic Investigation, 28(2), pp. 98–104. Available at: https://doi.org/10.1177/1040638715624736.
• Fabius, L.S. and Westermann, C.M. (2018) ‘Evidence-based therapy for atypical myopathy in horses’, Equine Veterinary Education, 30(11), pp. 616–622. Available at: https://doi.org/10.1111/eve.12734.

Current Vet is an educational podcast intended for veterinary students, veterinary professionals, and individuals with an interest in veterinary medicine.

All content provided in this podcast and its associated materials is for educational and informational purposes only. It is not intended as, and must not be considered a substitute for, professional veterinary advice, diagnosis, or treatment.

Any clinical cases discussed in this podcast are fictional, and are designed to reflect typical or likely clinical scenarios for educational purposes. They do not represent specific real-life cases, clients, or animals.

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