The Pharma Files
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Case File 14 — Bee Venom Therapy: The MS Miracle That Never Was

Dela

A woman with multiple sclerosis appeared on national television and said that bee stings had let her get out of her wheelchair. The phones started ringing, and they didn't stop. This episode follows the century-old idea behind bee venom therapy — from an Austrian physician's 1888 rheumatism paper to a Hungarian immigrant practicing in Manhattan to Charles Mraz, a Vermont beekeeper who spent six decades stinging patients for free and died in 1999 still believing he was helping them. The science behind it was never entirely implausible: bee venom contains a potent anti-inflammatory compound, MS is an autoimmune disease, and the logic seemed to track. Then researchers ran a controlled trial. For the full written case file, visit thepharmafiles.substack.com.



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