GLP-1 drugs like Ozempic and Wegovy have helped nearly 15% of Americans shed major weight—but stopping them often leads to significant regain, with up to 60% of lost weight returning within a year. Experts warn there’s no proven plan for safely discontinuing these meds, suggesting they may be intended for long-term use. To avoid rebound, patients should work with doctors to build a full lifestyle overhaul before stopping—focusing on nutrition, protein, strength training, sleep, and monitoring. “Microdosing” isn’t supported by science either. The real goal? Creating a sustainable, holistic strategy that addresses root causes like insulin resistance and keeps you healthy beyond the medication.
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