In the latest episode of Bioprocessing Unfiltered, Bill Whitford talks with Todd Przybycien about using precipitation as a continuous capture step for monoclonal antibody downstream processing, and why higher titers make the approach practical again. We dig into step change improvements in cost of goods, throughput, footprint, and sustainability, plus what it takes to control and automate a continuous process.
Join us to hear:
• Todd’s early downstream processing work and why “unconventional separations” matter
• Why precipitation was sidelined at low titers and why modern mAb titers change the efficiency
• How precipitation enables fully continuous capture and pairs with flow-through polishing
• Where the biggest gains show up, including dollars per gram, water usage per gram, and smaller facilities
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Covering both upstream and downstream processing, analytics, AI and digitization, cell and gene therapy and more, Bioprocessing Unfiltered is your insider's pass to the researchers tackling—and solving—the day-to-day challenges in the bioprocessing industry.
LINKS
https://www.bioprocessingsummit.com/
https://www.linkedin.com/groups/1982319/
Host Links
Bill Whitford: https://www.linkedin.com/in/william-whitford-00096612
Bioprocessing Unfiltered: Covering both upstream and downstream processing, analytics, AI and digitization, cell and gene therapy and more, Bioprocessing Unfiltered is your insider’s pass to the researchers tackling—and solving—the day-to-day challenges in the bioprocessing industry.
