First Principles
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EP60 - AlphaFold and the Origami of Life: Solving Biology’s Grandest Puzzle

Dela

For fifty years, biology faced a paradox that stumped the world’s brightest minds: how does a simple one-dimensional string of genetic code instantly fold into a complex three-dimensional machine? This episode deconstructs AlphaFold, the AI breakthrough that cracked the code, revealing how geometric deep learning and evolutionary history are rewriting the future of medicine.

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