Decoding Longevity with Dr. Nir Barzilai

What if you could actually delay the process of aging? Dr. Nir Barzilai hopes to identify interventions that could do just that. He believes a class of drugs known as gerotherapeutics could be real game changers.

Dr. Barzilai walks us through his pioneering research and explains why your biological age may actually be different from your chronological age. And we break down the buzziest trends in the longevity space.

Links to resources mentioned in this episode:

Cellergy Therapeutics

How to measure biological aging in humans

Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice

An Updated Prioritization of Geroscience- Guided FDA-Approved Drugs Repurposed to Target Aging

Comparative Effectiveness of Metformin Versus Sulfonylureas on Exceptional Longevity in Women With Type 2 Diabetes: Target Trial Emulation

The Super Ager Family Study

Nir Barziliai, MD, on what we can learn about longevity from SuperAgers and Centenarians

Cardiovascular advantages among the offspring of centenarians 

Lower all-cause, cardiovascular, and cancer mortality in centenarians' offspring

Reduced Prevalence and Incidence of Cognitive Impairment Among Centenarian Offspring

What You Should Know About NAD+ Supplements

Abstract 4168: NMN supplementation enhances proliferation and aggressiveness in UV-induced skin cancer

Note: In this show, we use “women” as shorthand for people with XX chromosomes. We understand sex and gender are more complex, and acknowledge the experiences we describe reach beyond that word.

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