If you’re heading into San Francisco this Labor Day weekend, brace for a major detour—Caltrans is shutting down all northbound lanes of Highway 101 through the Hospital Curve from Friday night at 11 p.m. until Monday morning at 6 a.m. Southbound lanes remain open, but drivers from the Peninsula or SFO should plan ahead with I-280 or public transit. The closure, part of a long-term upgrade of the 70-year-old stretch (covering 15+ lane miles), aims to minimize future disruptions by doing heavy work in one go. Traffic into SF is typically lighter on Labor Day, helping ease the strain. And it’s not over—another full northbound shutdown is scheduled for Sept. 18–21. Plan your route now and enjoy a less congested ride if you’re avoiding the city.
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