The 49ers’ pass rush is dangerously thin heading into the opener, with key players sidelined: Mykel Williams (ACL/meniscus) is out for at least a month, Sam Okuayinonu (foot injury) is on IR and won’t play against the Rams, leaving just three EDGE rushers active—Nick Bosa, Romello Height, and Keion White. To plug the gap, they’ve brought in Khalid Kareem from Atlanta’s practice squad, who’ll count for three weeks. The defense’s fate hinges on these moves as injuries pile up early.

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