The 49ers just pulled off a defensive shake-up, signing bruising lineman Khalid Kareem on a one-year deal while placing veteran Sam Okuayinonu on injured reserve. Kareem, a former Notre Dame standout with 13 sacks and 26 TFLs in college, brings elite size and proven production after stints with the Bengals, Colts, Bears, and Falcons. Okuayinonu, who started 12 games last season for SF, now makes way for fresh energy as the Niners gear up for the new campaign.
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