The Rams defense is absolutely terrifying for Week 1, even without Aaron Donald—thanks to the addition of Myles Garrett, who’s ready to go despite minor camp inflammation. This stacked front seven, already one of the league’s best, combined for over 200 pressures last season and now has Garrett ready to dominate. The 49ers’ offense, already struggling with run game efficiency, will face a gauntlet designed to force third-and-long situations—perfect for Garrett and Co. The secondary is equally formidable, with Trent McDuffie, Jaylen Watson, and Kamren Curl forming a relentless wall. While the linebackers (Landman, Speights) are decent against the run but shaky in coverage, the 49ers’ tight ends like George Kittle could exploit that. Still, the overall defensive firepower should be enough to stifle San Francisco—even on foreign soil. Expect a battle, but the Rams have the pieces to control it.

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