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1340-Sensitize Liver Cancer for Immunotherapy

Dela

This research identifies the enzyme SOAT1 as a primary driver of immune evasion and cancer recurrence in hepatocellular carcinoma (HCC). By analyzing human patient samples and mouse models, the authors demonstrate that SOAT1 supports tumor resilience by converting free cholesterol into esters, which maintains the metabolic and antioxidant capacity of cancer cells. Inhibiting this enzyme leads to c...去小宇宙查看完整单集简介
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