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1314-Genomic Instability in Neurodegenerative Disorders

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This research identifies a universal mechanism of genetic instability that links three major neurodegenerative disorders: ALS, FTD, and Alzheimer’s disease. By using single-cell whole-genome sequencing, scientists discovered that neurons in these diseased brains accumulate an excessive number of somatic mutations, most notably a specific signature of 2-base-pair deletions. These mutations are caus...去小宇宙查看完整单集简介
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