In this episode of In Conversation With, Larissa Otero, Senior Editor of The Lancet Regional Health – Europe, speaks with Dr Judith Bonnes and Dr Roos Edgar about their study on automated cardiac arrest detection using wrist-worn photoplethysmography devices. The discussion traces the journey from the DETECT-1A and DETECT-1B studies to the latest DETECT-1C validation, describing how a light-based sensor or photoplethysmography on the wrist can reliably detect the loss of pulse and trigger an automated alert — with potential implications for prompt detection of out-of-hospital cardiac arrest. The conversation also addresses the practical and logistical questions around real-world deployment, the limitations of the technology across diverse populations, and the unique ethical challenges of conducting research in end-of-life settings. The episode closes with what remains unanswered in the DETECT programme and the team's next steps
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