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🎙 EP 382: Claude Duet Proactive Agent & Small Team Designs Scorpion Antivenom

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Anthropic unveiled Claude Duet, a proactive AI agent powered by Opus 5.5 that operates independently in the cloud across 6,000+ connectors, running background workflows and surfacing prioritized briefings when human judgment is required. Meanwhile, a 5-person team working with Citrini Research and Claude generated 318,000 protein designs in just 64 hours, successfully binding 17 candidates to target toxins in wet-lab tests.

We’ll talk about:

  • Background cloud agent utilizing Opus 5.5 to monitor workflows, parse connected apps, and initiate actions via Shopify Shop Pay and Stripe Link.
  • Small-team experiment utilizing Claude to generate and test 318,000 protein designs, yielding 17 successful toxin-binding candidates in 64 hours.
  • Integration of GPT-6 Astra, GPT-6.1 Sol, and GPT-6 Luna onto Google Cloud alongside existing ecosystem models.
  • Bob McGrew’s new manufacturing automation startup reaching a $1.5B valuation after shrinking assembly documentation timelines from 10 hours to 15 minutes.

Keywords: Claude Duet, Claude design, Google Cloud, GPT-6 models.

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