In this #europcr 2026 interview, Davide Capodanno and Peter Libby discuss the role of inflammation in atherosclerosis and why many high-risk coronary plaques remain undetected by angiography. Advances in vascular biology have revealed how inflammation contributes to plaque instability and rupture, yet vulnerable plaques may appear angiographically insignificant. How can these lesions be identified before they lead to clinical events? What role do inflammation and emerging therapeutic targets play in reducing residual cardiovascular risk? Listen to this discussion to explore the mechanisms of plaque vulnerability and their implications for coronary artery disease management.
