Host Dr. Steve Nosworthy interviews Dr. Brad Rachman about his journey from a personal autoimmune crisis to decades in functional medicine and laboratory medicine, including his work with Genova Diagnostics. They discuss the history and evolution of functional medicine, how to choose meaningful tests, and how labs can both help and overwhelm clinicians.
Topics include Dr. Rockman’s origin story with ankylosing spondylitis, high-value lab markers (complement C3/C4, MMP‑9, TGF‑β1, GGT, oxidized LDL, CD4/CD8), stealth pathogens (EBV, Coxsackie, Chlamydia pneumoniae), dysglycemia assessment (HOMA, C‑peptide), and practical testing strategy versus data overload.
The conversation also covers clinical models and practice design (volume vs engagement), creating a patient roadmap and 10‑year risk analysis using AI, therapeutic priorities (diet, lifestyle, pro‑resolving mediators), and the philosophy of vitalism — trusting and stewarding the body’s innate ability to self‑regulate.
Listeners can expect practical takeaways on which tests are most actionable, how to communicate with patients about symptom flares, when to prioritize lifestyle over supplements, and how to design care that restores long‑term vitality and resilience.
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