In this episode of GI101, host Dr. Christina G. Gonzales, DMSc, MPAS, PA-C, reviews Toxic Megacolon, a life-threatening complication characterized by acute colonic dilation accompanied by systemic toxicity. You’ll learn to recognize key warning signs such as abdominal distention, pain, fever, tachycardia, and systemic illness, as well as its association with severe inflammatory bowel disease and infectious colitis. We’ll also cover important diagnostic findings, why colonoscopy and certain medications should be avoided, and the essentials of urgent management—including bowel rest, IV fluids, treatment of the underlying cause, and early surgical consultation. Perfect for PANCE prep and recognizing a GI emergency where rapid intervention matters.
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