Growth Factor Gold: How PDGF Is Changing Post-Procedure Skin Recovery

What exactly is PDGF (platelet-derived growth factor), and why is it becoming one of the hottest topics in regenerative aesthetics? This week, our hosts break down how PDGF works, how it compares to PRP, PRF, and exosomes, and why concentration and consistency matter for real results. Later, they're joined by Charlie Hee, PhD, Chief Scientific Officer at Lynch Regenerative Medicine (LRM), who explains the science behind recombinant PDGF-BB, how it's manufactured, and how it's used topically after procedures like microneedling, RF microneedling, laser resurfacing, and chemical peels to support healing and enhance results. Whether you're a patient considering post-procedure skincare or a provider curious about the future of regenerative aesthetics, this episode gives you the real science. Thanks for watching and be sure to follow for new episodes every Tuesday!

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00:00 – Cold Open 00:35 – Welcome Back & Banter 02:58 – Odd Places for Filler: Ears, Hands & Feet 11:03 – Setting Up Today's Topic: What Is PDGF? 12:54 – Why Truth in Aesthetics Matters (Avoiding Gimmicks) 15:24 – Commercial Break 16:24 – Welcome Charlie Hee, Chief Scientific Officer at LRM 16:58 – Charlie's Background: From Bioengineering to Aesthetics 22:40 – Taylor Joins the Conversation 22:58 – What Is Platelet-Derived Growth Factor (PDGF)? 25:44 – The "Trauma Team" Analogy Explained 26:29 – Where Does PDGF Come From? (Not From Blood Draws) 29:05 – Recombinant Technology & Why It Matters 32:14 – Breaking It Down: The Pig Kidney Analogy 35:21 – PDGF vs. PRP: The Consistency Problem 37:36 – The Wave Pool Analogy: Predictable vs. Variable Results 38:15 – Different PDGF Formulations for Different Uses 41:04 – Why Consistency Beats Trauma Team as We Age 43:39 – FDA Regulation: Cosmetic vs. Medical Classification 44:55 – Injectable PDGF Trend: What You Need to Know 48:04 – Best Use With CO2 Lasers & Deep Plane Facelifts 50:27 – Post-Procedure Aftercare Guidelines 52:37 – How Much Does It Cost? 53:27 – Could PDGF Help With Hair Loss? 55:36 – The Future of Regenerative Medicine & AI 57:41 – Final Thoughts & Thank You to Charlie 58:19 – Outro & Where to Follow Us