In this episode of JAMA+ AI Conversations, Roy Perlis, MD, MSc, and Haider Warraich, MD, sort out the prospects for AI-driven heart failure care that doesn't entail a human in the loop. Warraich is a program manager at ARPA-H, the Advanced Research Projects Agency for Health, responsible for ADVOCATE, an effort to support the development of AI to guide heart failure treatment, seeking to create AI agents that can pass muster with the FDA.

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