In this episode of the RevGenetics Podcast, Les and Amy discuss a promising breakthrough in longevity research: how you take your NMN supplement could dramatically impact its effectiveness. A recent study from Japan highlights the difference between sublingual administration (dissolving under the tongue) and oral swallowing. NMN plays a critical role in recharging NAD+, the vital cellular "battery" our bodies rely on for energy, repair, and overall health. When NMN is swallowed, much of it is broken down by the liver before ever reaching the rest of your cells. By letting the tablet dissolve under the tongue, NMN bypasses liver metabolism and enters the bloodstream directly. Tested on 14 healthy adult men, this method showed compelling results for significantly higher bioavailability and absorption. Could sublingual delivery be the key to maximizing your NMN regimen? Join us as we unpack the science and what these findings mean for the future of healthy aging.
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