Testosterone and Blood Clots: Is the Risk Actually Real?

With Dr. Abraham Morgentaler and Dr. Marianne Brandon

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In this episode, Dr. Brandon & Dr. Morgentaler talk about testosterone therapy, with a focus on the evidence surrounding whether testosterone increases the risk of blood clots, including DVT and pulmonary embolism.

00:00 Log Cabin Catch Up — Dr. Brandon and Dr. Morgentaler catch up about vacation, their matching log cabin surroundings, and kick off another episode of The Sex Doctors Podcast.

00:36 Listener Question: Testosterone For Women — A practicing PA asks why there still isn't an FDA-approved testosterone product specifically designed for women in the United States.

01:05 FDA Barriers And Breast Cancer Data — They discuss previous attempts to gain FDA approval and how concerns about testosterone converting to estrogen and potentially affecting breast cancer risk created demands for large, expensive safety studies.

02:29 Off Label Use And Market Economics — Dr. Morgentaler explains how women currently receive testosterone off-label and why inexpensive existing options make it difficult for pharmaceutical companies to justify the enormous cost of FDA approval.

06:27 Testosterone And Blood Clots Explained — They take a deep dive into whether testosterone increases the risk of DVT and pulmonary embolism, examining the TRAVERSE trial, COVID-related findings, hematocrit concerns, and evidence surrounding people already predisposed to clots.

18:38 Wrap Up And Send Questions — Dr. Brandon and Dr. Morgentaler close out the episode and invite listeners to subscribe and send in their own questions and comments.

#testosteronetherapy #womenhealthcare #sexdoctorspodcast