In this episode of the DDI of the Month podcast, Dr. David Burger dives into a critical topic: P-glycoprotein (P-gp)-mediated Drug-Drug Interactions with Dr. Leonie Bogaard. Join us as we explore the role of P-gp, a key transporter involved in drug absorption and elimination, and its impact on clinical outcomes.
In this episode, we discuss: • How P-gp modulation affects systemic drug exposure. • The challenges in managing DDIs due to overlap with enzymes like CYP3A4. • Practical recommendations for identifying and addressing P-gp-related DDIs in clinical settings.
Don’t miss this engaging discussion, featuring insights from recent research and expert recommendations on improving patient care while minimizing risks.
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