GLP-1s have changed the conversation on weight and metabolic health but the gut science, and life after stopping them, gets far less airtime. Sandra & Wagdy are joined by Dr. Linia Patel to unpack what's really happening in the body, the side effects nobody talks about and what comes next.
This episode covers:
- GLP-1 as a gut hormone and how the microbiome shapes our own natural production
- The gut-brain science behind appetite suppression, and whether these drugs alter the microbiome itself
- The digestive side effects nobody talks about and the red flags worth flagging to your prescriber
- Protecting fibre, nutrients and muscle mass on suppressed appetite
- Life after weight loss medication: why people stop and how to quieten food noise without it
- Whether GLP-1s risk replacing the deeper work on your relationship with food and much more.
So much of the GLP-1 conversation ends the moment someone starts the medication. We wanted to talk about everything else; the gut, the food noise and what actually happens when you stop.
About Dr. Linia Patel (PhD), RD
Dr Linia Patel is an award-winning Women’s Health Dietitian, Performance Nutritionist, and
Public Health Researcher with over 20 years of experience spanning sports nutrition, clinical
practice, and large-scale public health programmes. Author of the best-selling book Food for
Menopause, Linia has worked across diverse settings—from high-performance sport to NHS-
commissioned weight management services—translating science into practical strategies
that improve wellbeing and long-term health outcomes.
With the rapid rise of GLP-1 weight loss medications, much of her current clinical work
focuses on helping women navigate these treatments—whether starting, actively using, or
transitioning off them—while integrating lifestyle, nutrition, and behavioural strategies for
lasting success. Her approach is rooted in evidence, empowerment, and a deep
understanding of women’s unique health challenges across the lifespan.
Connect with Linia
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Grab a copy of Linia’s book: Life After Weight-Loss Medication
