The Carolina Panthers (2-2) come out of the bye in sole possession of first place in the NFC South, and they head to Philadelphia to face an Eagles team (2-3) that has lost three straight games. In this Week 6 preview, we break down everything you need to know before Sunday's 1:00 PM ET kickoff on CBS at Lincoln Financial Field.We start with the biggest storylines. Bryce Young leads the NFL at 317.0 passing yards per game, with 1,268 yards, 9 touchdowns and 2 interceptions, and Tetairoa McMillan is coming off a 14-catch, 192-yard game against Detroit. On the other side, Philadelphia lost 27-7 at Chicago, blew a 10-point fourth-quarter lead to the Rams, and lost 19-17 in London on a 57-yard field goal as time expired.Then we get into the matchups. Carolina's passing offense ranks second in the league in passing yards per game, and Next Gen Stats gives the Panthers the edge in 20 of 24 passing categories against an Eagles defense that ranks 26th in pass yards allowed and 30th in sack rate. But the Panthers allow 5.4 yards per rush, which is last in the league, and Saquon Barkley's hamstring is the biggest variable on the Philadelphia side. We also look at Jalen Hurts, who has almost stopped running by design, and at the Eagles' rebuilt offensive line after Lane Johnson's retirement and the Cam Jurgens trade.In this video:- Storylines and a recap of both teams' seasons- Coaching staffs, including the Eagles' new offensive coordinator Sean Mannion- Current depth charts for both teams- 2026 draft classes and offseason moves, including former Eagles Jaelan Phillips and AJ Dillon now in Carolina- Series history: the Eagles lead 9-4, and Carolina has not won at the Linc since 2018- IR report and this week's injury report- Player stats and defensive leaders- TeamRankings and Next Gen Stats matchup breakdowns- Odds: the Eagles are about 1 to 1.5 point favorites with a total of 41.5 to 42.5- NFC South watch- Three reasons the Panthers win and three reasons they lose- Our score prediction: Panthers 27, Eagles 19Which matchup decides this game, Bryce Young against the Eagles' pass rush or Saquon Barkley against the Panthers' run defense? Let us know in the comments.Follow Two Growls One Roar on X at @TGORPODCAST and on the web at twogrowlsoneroar.com.Two Growls One Roar is your home for Carolina Panthers coverage all season long — subscribe for game previews, recaps, and everything else Panthers football.#KeepPounding
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