In this episode, coauthors Daria Igudesman and Karen D. Corbin discuss their team’s recently published study, "Microbiota encroachment and a gut-adipose-liver axis in metabolic dysfunction-associated steatotic liver disease." This first-in-human study explores how changes in the gut microbiota may contribute to metabolic dysfunction through a gut-adipose-liver axis. The researchers found that colonic expression of insulin and lipid-related genes may link microbial encroachment in the colon with adipose tissue insulin resistance and the development of metabolic dysfunction-associated steatotic liver disease (MASLD). Tune in to learn how these findings offer new insights into the complex interplay between the gut microbiome and metabolic health.
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