Distinct brain atrophy patterns in anti-IgLON5 disease

Welcome to the 36th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. 

This episode features a discussion with senior author Dr Carsten Finke of the Brain article entitled: Brain atrophy patterns in anti-IgLON5 disease

We discuss a fascinating article which examines clinical and imaging data related to anti-Iglon5 disease. This valuable contribution to our understanding of this rare disease comprises data collected across multiple sites. Results identified distinct atrophy patterns in anti-IgLON5 disease, which closely mirror sites of pathophysiologic processes, including autoantibody binding and tau deposition.

Check out the full article on the Brain website as part of the March 2026 issue: https://doi.org/10.1093/brain/awaf256

This episode was co-hosted, edited and produced by Michael and Adam Handel, co-produced by Xin You Tai and Antonia Johnston, original music by Ammar Al-Chalabi.