In this episode we interview Dr. Johanna Olweus and Dr. Morten Milek Nielsen from University of Oslo about the use of T cell receptors (TCR’s) as immunotherapy against cancer.
Dr. Olweus’s group has been speadheading identifying TCRs that are specific for minute mutations in cancer cells, that can be used in adoptive T-cell-based therapies. We talk about what the therapy entails, how TCRs are discovered and go through several papers her group has published recently on using TCR-based therapies against leukemia.
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