Consider this your crash course on epigenetics with Dr. Peter W Laird.
Whether or not you've heard about epigenetics before, I guarantee you'll learn something new from this episode. This is the first of a series in which I'll be interviewing experts in health and science on their expertise, so if you have any specific topics you'd like us to cover, get in touch!
For any super curious nerds who want to go into a deeper dive on Epigenetics, here are a few interesting papers published by Dr. Laird and colleagues:
Knijnenburg, T. A., Wang, L., Zimmermann, M. T., Chambwe, N., Gao, G. F., Cherniack, A. D., Fan, H., Shen, H., Way, G. P., Greene, C. S., Liu, Y., Akbani, R., Feng, B., Donehower, L. A., Miller, C., Shen, Y., Karimi, M., Chen, H., Kim, P., Jia, P., … Wang, C. (2018). Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas. Cell reports, 23(1), 239–254.e6. https://doi.org/10.1016/j.celrep.2018.03.076
Shen, H., & Laird, P. W. (2013). Interplay between the cancer genome and epigenome. Cell, 153(1), 38–55. https://doi.org/10.1016/j.cell.2013.03.008
Shen, H., & Laird, P. W. (2012). In epigenetic therapy, less is more. Cell stem cell, 10(4), 353–354. https://doi.org/10.1016/j.stem.2012.03.012
