Carolina Reis Oliveira, PhD: Senescent Cells, Retinol Myths, and the Skin Barrier Body Connection - Longevity Optimization with Kayla Barnes-Lentz | Lyssna här

Most skincare is designed to improve how aging looks. But can it change what is happening inside the skin itself?

In this conversation, I sit down with Carolina Reis Oliveira, PhD, co-founder and CEO of OneSkin, to explore what actually drives skin aging at the cellular level. Carolina explains how senescent “zombie” cells, UV exposure, inflammation, hormonal changes and a weakened skin barrier affect how skin functions, not just how it looks.

Get OneSkin's new Rich Cream and the rest of the OS-01 line at:

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We break down the benefits and limitations of retinol, why chronic redness and flaking are not signs that a product is working better, and whether popular ingredients such as NAD+ precursors, methylene blue and GHK-Cu can penetrate the skin and remain stable. We also discuss collagen supplementation, red light therapy, hyperbaric oxygen, sauna, exercise, sun exposure and the relationship between skin-barrier health and systemic inflammation.

Carolina also shares the science behind OneSkin's OS-01 peptide and its new Face Rich Cream, including findings related to collagen, hyaluronic acid, elastin, filaggrin, hydration, firmness and fine lines.

In this conversation:

-Why many anti-aging products target visible symptoms rather than the biology of skin aging

-How senescent “zombie” cells contribute to inflammation and tissue decline

-How to use retinol without chronically damaging the skin barrier

-Why ingredient penetration, stability and formulation matter

-How skin-barrier dysfunction may affect inflammation throughout the body

-What collagen, red light, hyperbaric oxygen, sauna and exercise can do for the ski

- What OneSkin found when testing GHK-Cu copper peptides

-Why moisturizer alone may not solve age-related dryness

-How OS-01 is designed to target the underlying biology of skin aging

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