196 | Is Gluten REALLY That Bad For You? (Part 2)

Is gluten really wrecking your thyroid and brain? Part 2 breaks down the devastating effects of amylase trypsin inhibitors, where celiac disease ends and gluten/wheat sensitivity begubs, and the real evidence on gluten's cross-reactivity with Hashimoto's — plus how to test for it properly.

In Part 2 of this deep-dive, Dr. Steven Noseworthy picks up where Part 1 left off with the other non-gluten protein doing serious damage: amylase trypsin inhibitors (ATIs), which trigger their own transient leaky gut and — per 2020 research — remodel your gut microbiome the same way a course of antibiotics would. From there he draws the real line between celiac disease and non-celiac wheat sensitivity, walks through a November 2025 Lancet review on the gut-brain side of "gluten sensitivity," and takes an honest look at gluten's effect on blood flow to the brain and whether it actually cross-reacts with your thyroid in Hashimoto's. The episode closes with how to actually test for a gluten problem instead of guessing your way through an elimination diet.

📋 Episode page & full show notes: https://www.drnoseworthy.com/gluten-thyroid-part-2
🎧 Listen on Apple: https://podcasts.apple.com/us/podcast/inflammation-nation-with-dr-steven-noseworthy/id1587867271
🎧 Listen on Spotify: https://open.spotify.com/show/033uoJi0o86HDEoTYGI0n2

💬 Work with Dr. Noseworthy: https://www.drnoseworthy.com/contact

TIMESTAMPS
0:00 Recap of Part 1
4:11 Amylase Trypsin Inhibitors
7:31 Celiac Disease vs Wheat Sensitivity

12:10 Gluten's Antibiotic-like Impact on Gut Health

16:22 Gluten and Brain Function

18:29 Gluten Changes Blood Flow to Your Brain
21:17 Gluten and Thyroid Cross Reactivity
23:07 Next-Gen Testing for Gluten Sensitivity

#GlutenFree #Hashimotos #CeliacDisease #BrainFog #Microbiome #GutHealth #Inflammation