In this week’s episode of the Xtalks Life Science Podcast, host Vera Kovacevic, Editor-in-Chief at Xtalks, spoke with two experts from Boehringer Ingelheim: Itziar Canamasas, PhD, Global Head of Oncology and Senior Vice President, and Volker Teichgräber, MD, Senior Vice President and Head of Global Experimental Medicine Oncology.
The conversation focused on how precision oncology is changing the way advanced non-small cell lung cancer (NSCLC) is diagnosed, studied and treated. As molecular testing becomes increasingly important in lung cancer care, identifying specific genomic alterations early in the treatment journey can help inform treatment decisions and support more personalized approaches for patients.
In this episode, Itziar discusses how advanced NSCLC care has evolved over the past decade and why molecular testing is central to the future of precision oncology. She also shares her perspective on the unmet needs facing patients with rare molecularly defined forms of lung cancer, including HER2-mutant NSCLC.
Volker discusses the R&D considerations involved in studying rare genomic subtypes of NSCLC. He explains what researchers consider when translating early clinical findings into later-stage studies.
The conversation also explores how clinical trial design is evolving in precision oncology, including the need to balance scientific rigor with the practical realities of studying rare patient groups.
Itziar and Volker also discuss what may matter most for improving outcomes in advanced NSCLC and other molecularly defined cancers, from earlier testing and targeted treatment strategies to continued advances in translational medicine, biomarkers and clinical research.
Tune in to learn more about precision oncology in advanced NSCLC, the role of molecular testing and the challenges of developing targeted therapies for rare genomic subtypes.
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